N-Methylnicotinamide CAS 114-33-0

N-Methylnicotinamide (CAS 114-33-0) is an N-methylated nicotinamide derivative with the molecular formula C7H8N2O, commonly used as a reference compound in metabolite and biochemical research.

Metabolite Research: Used as a niacin metabolite analogue in NAD+ metabolism, cellular signaling, and biochemical pathway studies.

Defined Pyridine Scaffold: N-Methylpyridine-3-carboxamide structure suitable for heterocyclic synthesis and drug discovery research.

Analytical Reference: Assay ≥97.0%, suitable as a reference or impurity standard in biological and pharmaceutical analysis.

Convenient Solid Form: White to off-white solid, suitable for laboratory weighing, dissolution, and analytical workflows.

Pharmaceutical Synthesis: Serves as an essential building block in the development of targeted therapeutic drug candidates, enzyme inhibitors, and metabolic derivatives.

Biochemical Research: Utilized as a standard reference compound and endogenous metabolite analogue for cellular signaling and metabolic pathway studies.

Agrochemical Intermediates: Acts as a reactive heterocyclic precursor utilized in formulating specialized crop protection agents and systemic compounds.

Specialty Organic Chemistry: Applied in amide coupling reactions and targeted functionalization of pyridine scaffolds for advanced material synthesis.

Flexible Order Quantities: Accommodates R&D sampling requirements starting at 1 kg, scaling up to standard 25 kg fiber drums and custom industrial quantities.

Custom Route Optimization: Dedicated organic synthesis teams available for scale-up optimization, custom derivative preparation, and impurity standard isolation.

Industrial Packaging Standards: Packed in dual-layer food-grade polyethylene liners sealed inside robust UN-approved fiber drums to guarantee transit security.

Global Freight Management: Compliant with IMDG, IATA, and ADR transport regulations, supporting smooth customs clearance and air/sea freight routing worldwide.

Spectroscopic Screening: 1H/13C NMR and FT-IR help identify structural anomalies, synthetic byproducts, and functional group changes.

Heavy Metal & Inorganic Testing: ICP analysis monitors trace metals and inorganic contaminants to support applicable quality requirements.

Residual Solvent Monitoring: Headspace GC is used to evaluate residual organic solvents in accordance with applicable ICH requirements.

Retention Sample Management: Representative samples are retained for batch traceability, quality review, and reproducibility assessment.

Lot-Specific Certificate of Analysis: Every commercial shipment includes a comprehensive COA detailing actual analytical test values for purity, moisture, and melting point.

Compliant Safety Data Sheet: Fully updated GHS-compliant SDS available, identifying necessary handling precautions for skin and eye irritation risks (GHS07).

Regulatory Support Documentation: Complete assistance provided for REACH compliance statements, origin declarations, and heavy metal testing certificates.

Instrumental Testing: Batches are tested in-house utilizing calibrated HPLC, GC-MS, FT-IR, and automated titration instruments.

Traceable Lot Management: Comprehensive raw material documentation, production parameter logs, and archived retention samples maintained for a minimum of 3 years.

Certified Quality Systems: Operations adhere strictly to ISO 9001 (Quality Management) and ISO 14001 (Environmental Management) standards.

Reproducible Batch Performance: Standardized operating procedures ensure minimal batch-to-batch variation in appearance, assay value, and reactivity profile across multi-year purchasing cycles.

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