4,4'-Oxybis(phenyl isocyanate) is an aromatic diisocyanate containing two reactive isocyanate groups, with a molecular formula of C14H8N2O3 and molecular weight of 252.22 g/mol. It is used as a reactive intermediate in polyurethane and specialty polymer synthesis.
Key Specifications
|
Appearance |
Colorless liquid |
|
Assay |
98.0% Min |
If required, the latest specifications and analysis report will be made available.
Packaging, Storage and delivery
|
Standard Packaging |
suitable or custom packaging upon request |
|
Storage Conditions |
Store in a cool, dry, well-ventilated area. Keep container tightly sealed under inert atmosphere if long-term storage is required |
|
Transport information |
Not regulated as a dangerous good |
|
Shipping Methods |
DHL, FedEx, air freight or sea freight (IMDG/IATA compliant) |
Product Specifications
|
Item |
Specification |
|
Product Name |
4,4'-Oxybis(phenyl isocyanate) |
|
CAS No. |
4128-73-8 |
|
Molecular Formula |
C14H8N2O3 |
|
Molecular Weight |
252.22 g/mol |
|
Assay |
≥98.0% |
|
Appearance |
Colorless Liquid |
|
Chemical Type |
Aromatic Diisocyanate |
|
Functional Groups |
Two Isocyanate (-NCO) Groups |
|
Synonyms |
4,4'-Diisocyanatodiphenyl Oxide; 4,4'-Diisocyanatodiphenyl Ether |
|
COA |
Available |
|
SDS |
Available |
Physical & Chemical Properties

Visual State: Formulated as a colorless liquid state under ambient room conditions.
Assay Threshold: Maintained at a minimum purity level of 98.0% as measured via standard analytical methods.
Chemical Reactivity: Contains reactive isocyanate groups that can readily react with compounds containing active hydrogen, including water, alcohols, and amines.
Applications
Pharmaceutical Research: Utilized as a reactive intermediate in synthesizing compounds such as lipid-conjugated Smac analogs investigated in human breast cancer cell line studies.
Macroscopic Synthesis: Functions as a precursor in academic and industrial pathways targeting novel chiral macrocycles and specialized polymer networks.
Chemical Intermediates: Acts as a reactive building block in multi-step organic synthesis where dual isocyanate functionality is required.
Regulatory & Compliance
Quality Systems: Manufactured in facilities certified to ISO 9001:2015 quality standards and ISO 14001 environmental management frameworks.
Sustainability Standards: Produced by an EcoVadis Gold-rated organization, satisfying corporate green supply chain and ESG procurement requirements.
Documentation Support: Comprehensive Safety Data Sheets (SDS), certificates of origin, and regulatory documentation provided to streamline import customs clearance.
Quality Control Process
Raw Material Verification: Incoming raw materials are checked against approved specifications before production to support consistent starting-material quality.
In-Process Monitoring: Key reaction and processing parameters are monitored according to established manufacturing procedures and product specifications.
Analytical Testing: Finished batches are tested using analytical instruments including HPLC and GC-MS, with assay, moisture content, and appearance evaluated as applicable.
Batch Traceability: Production records and analytical results are maintained for batch-level traceability throughout manufacturing and shipment.
COA Documentation: A batch-specific Certificate of Analysis (COA) can be provided with applicable analytical results and product specifications.
Manufacturing & Supply Capability
Multi-Site Manufacturing: Manufacturing bases in Zhejiang, Jiangsu, and Shandong support laboratory, pilot-scale, and commercial chemical production.
Scale-Up Capability: Production can be developed from kilogram-scale pilot batches to multi-ton annual capacity according to product and process requirements.
Production Equipment: Facilities include glass-lined reactors, hydrogenation systems, cryogenic equipment, pilot equipment, and small-scale testing systems.
Technical Support: A team of 15+ organic chemists supports route design, process optimization, scale-up, and custom synthesis projects.
Packaging, Storage and delivery
Packaging Options: Standard industrial packaging configurations(1kg, 5kg, 25kg, 200kg) or customized packaging solutions available upon formal request.
Storage Guidelines: Store in a cool, dry, and well-ventilated area. Keep containers tightly sealed under an inert atmosphere for extended storage stability.
Transport Classification: Not classified as a regulated dangerous good for standard transit; shipped securely via air freight (IMDG/IATA compliant), sea freight, DHL, or FedEx.

Spectrum



FAQ
Q: Can I request a sample before placing a bulk order?
A: Yes. Samples of approximately 5–100 g can be arranged for preliminary evaluation, subject to availability and shipping requirements.
Q: What is the minimum order quantity (MOQ)?
A: The MOQ can be 1 kg for R&D orders. For larger quantities, commercial pricing can be discussed based on the required volume.
Q: What information is needed for a bulk quotation?
A: Buyers can provide the required quantity, target specification, packaging preference, destination country, and expected delivery schedule to support quotation preparation.
Q: What is the typical lead time for orders?
A: In-stock orders can typically ship within 7 days, while custom synthesis generally takes 4–6 weeks, depending on quantity and specifications.
Q: Can the product be supplied for R&D and pilot-scale evaluation?
A: Yes. Supply can be discussed for laboratory R&D and pilot-scale requirements, with quantity and technical specifications confirmed before order placement.
Q: Can you support customized product requirements?
A: Yes. Custom requirements can be evaluated based on target specifications, batch quantity, analytical requirements, packaging, and intended market.
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