4,4'-Oxybis(phenyl isocyanate) CAS 4128-73-8

4,4'-Oxybis(phenyl isocyanate) CAS 4128-73-8

4,4'-Oxybis(phenyl isocyanate) is an aromatic diisocyanate containing two reactive isocyanate groups, with a molecular formula of C14H8N2O3 and molecular weight of 252.22 g/mol. It is used as a reactive intermediate in polyurethane and specialty polymer synthesis.

Product Introduction

4,4'-Oxybis(phenyl isocyanate) is an aromatic diisocyanate containing two reactive isocyanate groups, with a molecular formula of C14H8N2O3 and molecular weight of 252.22 g/mol. It is used as a reactive intermediate in polyurethane and specialty polymer synthesis.

 

Key Specifications

 

Appearance

Colorless liquid

Assay

98.0% Min

If required, the latest specifications and analysis report will be made available.

 

Packaging, Storage and delivery

 

Standard Packaging

suitable or custom packaging upon request

Storage Conditions

Store in a cool, dry, well-ventilated area. Keep container tightly sealed under inert atmosphere if long-term storage is required

Transport information

Not regulated as a dangerous good

Shipping Methods

DHL, FedEx, air freight or sea freight (IMDG/IATA compliant)

Product Specifications

 

Item

Specification

Product Name

4,4'-Oxybis(phenyl isocyanate)

CAS No.

4128-73-8

Molecular Formula

C14H8N2O3

Molecular Weight

252.22 g/mol

Assay

≥98.0%

Appearance

Colorless Liquid

Chemical Type

Aromatic Diisocyanate

Functional Groups

Two Isocyanate (-NCO) Groups

Synonyms

4,4'-Diisocyanatodiphenyl Oxide; 4,4'-Diisocyanatodiphenyl Ether

COA

Available

SDS

Available

 

Physical & Chemical Properties

 

f-CAS-4128-73-8-C14H8N2O3

Visual State: Formulated as a colorless liquid state under ambient room conditions.


Assay Threshold: Maintained at a minimum purity level of 98.0% as measured via standard analytical methods.


Chemical Reactivity: Contains reactive isocyanate groups that can readily react with compounds containing active hydrogen, including water, alcohols, and amines.

 

Applications

 

Pharmaceutical Research: Utilized as a reactive intermediate in synthesizing compounds such as lipid-conjugated Smac analogs investigated in human breast cancer cell line studies.


Macroscopic Synthesis: Functions as a precursor in academic and industrial pathways targeting novel chiral macrocycles and specialized polymer networks.


Chemical Intermediates: Acts as a reactive building block in multi-step organic synthesis where dual isocyanate functionality is required.

 

Regulatory & Compliance

 

Quality Systems: Manufactured in facilities certified to ISO 9001:2015 quality standards and ISO 14001 environmental management frameworks.


Sustainability Standards: Produced by an EcoVadis Gold-rated organization, satisfying corporate green supply chain and ESG procurement requirements.


Documentation Support: Comprehensive Safety Data Sheets (SDS), certificates of origin, and regulatory documentation provided to streamline import customs clearance.

 

Quality Control Process

 

Raw Material Verification: Incoming raw materials are checked against approved specifications before production to support consistent starting-material quality.


In-Process Monitoring: Key reaction and processing parameters are monitored according to established manufacturing procedures and product specifications.


Analytical Testing: Finished batches are tested using analytical instruments including HPLC and GC-MS, with assay, moisture content, and appearance evaluated as applicable.


Batch Traceability: Production records and analytical results are maintained for batch-level traceability throughout manufacturing and shipment.


COA Documentation: A batch-specific Certificate of Analysis (COA) can be provided with applicable analytical results and product specifications.

 

Manufacturing & Supply Capability

 

Multi-Site Manufacturing: Manufacturing bases in Zhejiang, Jiangsu, and Shandong support laboratory, pilot-scale, and commercial chemical production.


Scale-Up Capability: Production can be developed from kilogram-scale pilot batches to multi-ton annual capacity according to product and process requirements.


Production Equipment: Facilities include glass-lined reactors, hydrogenation systems, cryogenic equipment, pilot equipment, and small-scale testing systems.


Technical Support: A team of 15+ organic chemists supports route design, process optimization, scale-up, and custom synthesis projects.

 

Packaging, Storage and delivery

 

Packaging Options: Standard industrial packaging configurations(1kg, 5kg, 25kg, 200kg) or customized packaging solutions available upon formal request.


Storage Guidelines: Store in a cool, dry, and well-ventilated area. Keep containers tightly sealed under an inert atmosphere for extended storage stability.


Transport Classification: Not classified as a regulated dangerous good for standard transit; shipped securely via air freight (IMDG/IATA compliant), sea freight, DHL, or FedEx.

 

s-CAS-4128-73-8

 

Spectrum

 

t-cas-4128-73-8-C14H8N2O3

 

certificate

manufacturer

 

FAQ

 

Q: Can I request a sample before placing a bulk order?

A: Yes. Samples of approximately 5–100 g can be arranged for preliminary evaluation, subject to availability and shipping requirements.

Q: What is the minimum order quantity (MOQ)?

A: The MOQ can be 1 kg for R&D orders. For larger quantities, commercial pricing can be discussed based on the required volume.

Q: What information is needed for a bulk quotation?

A: Buyers can provide the required quantity, target specification, packaging preference, destination country, and expected delivery schedule to support quotation preparation.

Q: What is the typical lead time for orders?

A: In-stock orders can typically ship within 7 days, while custom synthesis generally takes 4–6 weeks, depending on quantity and specifications.

Q: Can the product be supplied for R&D and pilot-scale evaluation?

A: Yes. Supply can be discussed for laboratory R&D and pilot-scale requirements, with quantity and technical specifications confirmed before order placement.

Q: Can you support customized product requirements?

A: Yes. Custom requirements can be evaluated based on target specifications, batch quantity, analytical requirements, packaging, and intended market.

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