Di-p-Anisoyl-D-tartaric Acid (CAS 191605-10-4) is a chiral D-tartaric acid derivative containing two p-methoxybenzoyl groups. Its defined stereochemistry and specific rotation support its use in chiral resolution and the preparation of optically enriched intermediates.
Chemical Specifications
|
Appearance |
White to off-white powder or crystal |
|
Purity |
98.0%min |
|
Water |
0.5%max |
|
Specific rotation |
+165.0- +171.0 |
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Product Specifications
|
Parameter |
Specification |
|
Product Name |
Di-p-Anisoyl-D-tartaric Acid |
|
CAS No. |
191605-10-4 |
|
EINECS |
471-150-6 |
|
Synonyms |
(+)-Bis(4-methoxybenzoyl)-D-tartaric Acid; (+)-Di-p-anisoyl-D-tartaric Acid |
|
IUPAC Name |
(2S,3S)-2,3-Bis((4-methoxybenzoyl)oxy)succinic acid |
|
Molecular Formula |
C20H18O10 |
|
Molecular Weight |
418.35 g/mol |
|
Appearance |
White to off-white powder or crystal |
|
Purity |
≥98.0% |
|
Water |
≤0.5% |
|
Specific Rotation |
+165.0° to +171.0° |
Key Properties
Optical Activity: Exhibits a defined specific rotation range of +165.0° to +171.0°, providing a useful parameter for batch identification and stereochemical quality control.
High Chemical Purity: Available with a purity of ≥98.0%, suitable for chiral synthesis, resolution studies, pharmaceutical intermediate development, and related research applications.
Low Moisture Content: Controlled water content of ≤0.5% helps maintain consistent material quality during storage, handling, and downstream synthetic processes.
Applications
Active Pharmaceutical Ingredients (APIs): Critical chiral intermediate and resolving agent used in the synthesis of cardiovascular, antiviral, and central nervous system (CNS) therapeutics.
Chiral Synthons: Serves as a foundational precursor for building enantiopure nitrogen-containing heterocycles and complex chiral building blocks.
Agrochemical Intermediates: Utilized in the preparation of specialized enantiomerically enriched agrochemical active ingredients and pyrethroid precursors.
Drug Discovery R&D: Deployed in academic and industrial laboratories for asymmetric synthesis method development and optical resolution screening.
Custom Synthesis & Bulk Supply
Scale Capabilities: CDMO services managed by an R&D team of 15+ organic chemists, supporting kilogram-scale pilot runs up to multi-ton commercial production.
Reaction Capabilities: Technical capacity covering catalytic hydrogenation, asymmetric synthesis, fluorination, and organometallic reactions.
Supply Arrangements: Tailored bulk supply agreements, scheduled shipments, and dedicated customer account management for B2B procurement partners.
Research Infrastructure: Utilization of laboratory facilities at Zhejiang University and Zhejiang Industry University for route scouting and process optimization.
Quality Assurance
Analytical Testing: Every production batch undergoes multi-stage inspection and testing using high-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS) to ensure consistent batch-to-batch quality.
Quality Management: Manufacturing facilities operate under ISO 9001:2015 quality management principles, backed by full batch tracking documentation from raw material input through final QA release.
Technical & Compliance Documents: Batch-specific Certificates of Analysis (COA) containing purity, water content, and specific rotation data are provided prior to shipment alongside comprehensive Safety Data Sheets (SDS).
Regulatory Support: Complete documentation packages include REACH compliance data, origin statements, and non-hazardous transport declarations to support global regulatory audits and customs clearance.
Packaging & Storage
Standard Packaging: Packed in robust 20 kg/drum industrial fiber or plastic drums designed to prevent moisture ingress and contamination.
Transport Classification: Shipped globally as a non-hazardous chemical via air freight, sea freight, DHL, FedEx, and UPS with full customs support.
Storage Conditions: Store in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight, moisture, and incompatible oxidizing agents.
Global Logistics Support: Specialized hazardous/non-hazardous packaging complying with IATA and IMDG standards, backed by real-time shipment tracking and transit insurance.
Spectrum
FAQ
Q: What is the minimum order quantity (MOQ) for routine production orders?
A: Standard order quantities generally start at one 20 kg drum, though trial quantities for laboratory evaluation can be evaluated on a case-by-case basis.
Q: What is the typical lead time for standard delivery orders?
A: In-stock materials typically ship within 3 to 5 business days, while custom or larger volume schedules are established during order confirmation based on active production capacity.
Q: What international payment methods are accepted for commercial transactions?
A: Accepted payment terms include Telegraphic Transfer (T/T), Letter of Credit (L/C) at sight, and PayPal for qualifying small-scale sample transactions.
Q: Can analytical testing methods be customized to align with client-specific pharmacopeial standards?
A: Analytical protocols can be reviewed against specific client compendial requirements during contract setup to determine feasibility and alignment.
Q: Are customized packaging sizes available aside from the standard 20 kg drum?
A: Alternative packaging configurations can be discussed depending on specific handling needs or pilot-scale processing requirements.
Q: How are customs clearance documents coordinated for shipments into regulated regions like the EU or North America?
A: Commercial invoices, packing lists, origin statements, and non-hazardous transport declarations are prepared and included with shipments to support local customs entry.
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