2-Bromo-5-tert-butyl-pyridine CAS 1142197-19-0 is a brominated pyridine compound used as an intermediate and building block in organic synthesis.
Chemical specifications
|
Appearance |
Colorless to light yellow transparent liquid |
|
Purity(GC) |
98.0% min |
|
Water |
0.5% max |
|
Total impurity |
2.0% max |
|
Single impurity |
1.0% max |
Applications
Pharmaceutical Synthesis
Used as a pyridine building block in the development and synthesis of pharmaceutical intermediates and active compounds.
Agrochemical Synthesis
Used as an organic intermediate for the preparation of nitrogen-containing compounds and agrochemical intermediates.
Specialty Organic Synthesis
Suitable for research, process development, and synthetic routes requiring a brominated pyridine building block.
Quality Control & Batch Consistency
Raw Material Control - Key starting materials are checked against approved purchasing specifications before production. Materials that do not meet the required quality criteria are not released for manufacturing.
Process Control - Critical reaction parameters are monitored during production to keep the process within defined operating conditions and reduce variation between batches.
Intermediate Monitoring - In-process samples are analyzed at applicable production stages to monitor reaction progress and identify potential deviations before the material reaches the final stage.
Final Product Testing - The finished product is tested against the approved specification before shipment. Applicable quality controls include assay, water content, total impurities, and individual impurity levels.
Analytical Verification - Test results are reviewed against the defined acceptance criteria to confirm that the batch meets the required quality standard before release.
Batch Release - A batch is released only after production and quality control results have been reviewed and confirmed to meet the approved requirements.
Batch Traceability - Production and analytical records are maintained for each batch, allowing the supplied material to be traced back to its manufacturing and testing records when required.
Analytical Documentation
Batch-specific quality documentation can be provided to support customer qualification and incoming quality control.
COA - Available for shipped batches with corresponding test results.
SDS - Provided for product handling, storage, and regulatory review.
Specification Sheet - Available for customer qualification and purchasing approval.
Analytical Report - Additional analytical information can be provided when required.
Spectrum - Available for product identification and technical evaluation upon request.
Customization Options
Purity
Standard 98%+ / Customer-specified purity
Impurity Control
Standard impurity limits / Customer-specified individual impurity limits
Testing
Standard QC / Additional analytical testing
Packaging
10 kg drum / 20 kg drum / Custom packaging
Labeling
Standard label / Customer-specific label
Packaging & Delivery
|
Order Type |
Packaging |
Typical Use |
|
Sample |
Small laboratory package |
R&D, laboratory testing, initial evaluation |
|
Small Order |
10 kg/drum |
Trial orders and small-volume procurement |
|
Bulk Order |
20 kg/drum |
Routine commercial supply |
|
Custom Order |
Customer-specified package |
Special handling, storage, or project requirements |
Container: Export-suitable drum packaging
Inner Protection: Sealed to prevent leakage and contamination
Product Label: Product name, CAS No., net weight, batch No., and other required information
Batch Identification: Each package is traceable to the corresponding production batch
Custom Packaging: Package size, labeling, and identification requirements can be arranged for qualified orders
Pre-Shipment Check: Quantity, container condition, sealing, labeling, and batch information are checked before dispatch
|
Shipping Method |
Recommended For |
Delivery Arrangement |
|
Express Courier |
Samples and small orders |
DHL, FedEx, UPS |
|
Air Freight |
Time-sensitive commercial orders |
Airport-to-door or agreed destination |
|
Sea Freight |
Larger-volume orders |
Suitable for bulk shipments |
|
Customer's Forwarder |
Customers with nominated logistics partners |
Shipment coordinated with designated forwarder |
Order Process & Payment
Requirement Confirmation
Confirm quantity, specification, packaging, destination, and required documentation.
Quotation
A quotation is prepared according to the confirmed order requirements and delivery conditions.
Sample or Order Confirmation
Samples can be arranged for evaluation, or production can proceed after commercial order confirmation.
Production & Quality Control
The batch is manufactured and tested according to the confirmed specification.
Shipment
After quality release, the qualified batch is packed and shipped with the required documentation.
Payment Methods
T/T, L/C at sight, and PayPal for applicable orders.
Spectrum
FAQ
Q: What is the shelf life of 2-Bromo-5-tert-butyl-pyridine?
A: The shelf life is determined according to the product's stability data and storage conditions. The applicable shelf-life information can be provided with the product documentation.
Q: How should 2-Bromo-5-tert-butyl-pyridine be stored?
A: The product should be stored according to the conditions specified in its current SDS and product documentation. Customers can request the applicable storage and handling requirements before purchase.
Q: Is 2-Bromo-5-tert-butyl-pyridine suitable for process development?
A: Yes. It can be evaluated as a brominated pyridine intermediate during laboratory research, route development, and process development before scale-up.
Q: Can you provide a pre-shipment sample from the production batch?
A: Production-batch samples can be discussed for customers who need material representative of the commercial supply for qualification or process evaluation.
Q: Can this product be used for pharmaceutical intermediate development?
A: Yes. 2-Bromo-5-tert-butyl-pyridine can serve as a pyridine building block in synthetic routes for pharmaceutical intermediate and active-compound development.
Q: How can I evaluate whether this material is suitable for my synthesis route?
A: Customers can provide their required specification, application requirements, and analytical acceptance criteria for technical review before placing an order.
Q: Can you support recurring demand for 2-Bromo-5-tert-butyl-pyridine?
A: Yes. For projects with recurring demand, estimated annual or periodic consumption can be discussed to support production planning and supply continuity.
Q: What information should I provide when requesting a quotation?
A: For an accurate quotation, it is useful to provide the required quantity, target delivery date, destination country, purchasing specification, and any special quality or packaging requirements.
Q: How do you handle product specification changes for repeat orders?
A: Any agreed changes to product specifications should be confirmed before production. The applicable requirements can then be incorporated into the production and quality-control instructions for the relevant order.
Q: Can you support supplier qualification for 2-Bromo-5-tert-butyl-pyridine?
A: Yes. Product specifications, quality documentation, analytical information, and other supplier-qualification materials can be provided as required for customer evaluation.
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